Gabriel C. E. Loke, Ching Han Toh, Sherilyn Z. H. Liew, Ryan S. Y. C. Tan, Daniel J.M. Ang
Journal of Clinical Question
Articles in Press
Keith Lawrence Uy, Alexandra Hong, Alyssa Leo, Gary Chu
Latest Articles
Xianjihao Yu, Fuzhe Li, Xin Zhou, Le Yu, Jing Qi
Maeda Toshiyoshi, Jingchao Ma, Ye Zhao
Hao Chen, Yang Gong
En Wang, Ayaka Yao, Maho Sasaki, Ryota Tanaka, Mohamed Hassanein, Yushi Fujiwara, Taigo Tokuhara
Aleena Kuriakose, Salem Gogah, Elina Beleva
Long-Hua Lu, Ze-Yang Zeng, Zi-Qi Guan, Luan Wang, Xiao-Ying Qi, Shu-Ling Zhang
Yong-Mei Guo, Yan Zhao, Toshiyoshi Maeda, Nouhaila Ezzaoui, Chinwebudu M. Melford
Hisashi Nagai
Aim and Scope
Aim: The Journal of Clinical Question aims to advance the understanding and application of clinical questions in healthcare practice. Well-formulated clinical questions provide the foundation for clinical recommendations, guideline development, and evidence-based decision-making. Recognizing that guideline development can be time- and resource-intensive, the journal provides a platform for generating and disseminating timely, question-centered evidence. By promoting the systematic evaluation of clinically relevant questions, the journal supports the advancement of evidence-based medicine and the translation of research into patient-centered care.
Scope: The journal publishes original research, systematic reviews, meta-analyses, review articles, short communications, and case reports addressing well-defined questions relevant to clinical research or healthcare practice. Submissions emphasize methodological rigor, clinical relevance, and applicability to healthcare practice.
Editor-in-Chief

Richard S. Isaacs, MD, FACS, is the Editor-in-Chief of the Journal of Clinical Question. He is a nationally recognized physician executive, academic leader, and board-certified head and neck surgeon with extensive experience in medical education, healthcare innovation, and organizational leadership.
Dr. Isaacs most recently served as Dean, Professor of Otolaryngology, Chief Academic Officer, and Senior Vice President of Medical Affairs at California Northstate University, where he helped guide the College of Medicine to full LCME accreditation in June 2025. Previously, he served as Chief Executive Officer of The Permanente Medical Group and The Mid-Atlantic Permanente Medical Group, leading approximately 12,000 physicians and 45,000 healthcare professionals serving more than 5.4 million members.
His editorial vision emphasizes scientific rigor, clinically meaningful research, multidisciplinary collaboration, and the translation of evidence into improved patient care.